Corticotropin Releasing Factor (CRF) (Human, Rat, Mouse, Canine, Feline) – RIA Kit

The Corticotropin Releasing Factor (CRF) (Human, Rat, Mouse, Canine, Feline) – RIA Kit (Catalog #RK-019-06) is a research reagent supplied by Phoenix Peptide under our specialized ELISA Kits – Assay Kits – RIA Kits category. This item is offered at a regular price of $942 for a package size of 125 tubes.

Storage, Handling & Operational Notes

Transport & Regulatory Notes: This package conforms to the 49 CFR173.421 for expected radioactive material limited quantity, N.O.S. UN2910.

References & Citations: Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters. Lu WD, Funkelstein L, Toneff T, Reinheckel T, Peters C, Hook V. J Neurochem. 2012122(3):512-22. Fetal undernutrition induces overexpression of CRH mRNA and CRH protein in hypothalamus and increases CRH and corticosterone in plasma during postnatal life in the rat. Núñez H, Ruiz S, Soto-moyano R, et al. Neurosci Lett. 2008448(1):115-9. Differential regulation of prostaglandin production mediated by corticotropin-releasing hormone receptor type 1 and type 2 in cultured human placental trophoblasts. Gao L, Lu C, Xu C, Tao Y, Cong B, Ni X. Endocrinology. 2008149(6):2866-76. Amygdala protein kinase C epsilon regulates corticotropin-releasing factor and anxiety-like behavior. Lesscher HM, Mcmahon T, Lasek AW, et al. Genes Brain Behav. 20087(3):323-33. Influence of f-MLP, ACTH(1-24) and CRH on in vitro chemotaxis of monocytes from centenarians. Genedani S, Filaferro M, Carone C, et al. Neuroimmunomodulation. 200815(4-6):285-9. Neuroactive steroids modulate HPA axis activity and cerebral brain-derived neurotrophic factor (BDNF) protein levels in adult male rats. Naert G, Maurice T, Tapia-arancibia L, Givalois L. Psychoneuroendocrinology. 200732(8-10):1062-78. Novel in vitro perfusion system for the determination of hypothalamic-pituitary-adrenal axis responses. Moidel MA, Belz EE, Czambel RK, Rubin RT, Rhodes ME. J Pharmacol Toxicol Methods. 200653(3):264-71. Continuous i.c.v. infusion of brain-derived neurotrophic factor modifies hypothalamic-pituitary-adrenal axis activity, locomotor activity and body temperature rhythms in adult male rats. Naert G, Ixart G, Tapia-arancibia L, Givalois L. Neuroscience. 2006139(2):779-89. Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington’s disease. Björkqvist M, Petersén A, Bacos K, et al. Hum Mol Genet. 200615(10):1713-21. Cocaine experience establishes control of midbrain glutamate and dopamine by corticotropin-releasing factor: a role in stress-induced relapse to drug seeking. Wang B, Shaham Y, Zitzman D, Azari S, Wise RA, You ZB. J Neurosci. 200525(22):5389-96. Plasma and hypothalamic peptide-hormone levels regulating somatotroph function and energy balance in fed and fasted states: a comparative study in four strains of rats. Kappeler L, Zizzari P, Grouselle D, Epelbaum J, Bluet-pajot MT. J Neuroendocrinol. 200416(12):980-8. Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice. Sudo N, Chida Y, Aiba Y, et al. J Physiol (Lond). 2004558(Pt 1):263-75. Effects of electro-acupuncture on corticotropin-releasing factor in rats with experimentally-induced polycystic ovaries. Stener-victorin E, Lundeberg T, Waldenström U, Bileviciute-ljungar I, Janson PO. Neuropeptides. 200135(5-6):227-31. Atrial natriuretic hormone, vessel dilator, long-acting natriuretic hormone, and kaliuretic hormone decrease the circulating concentrations of CRH, corticotropin, and cortisol. Vesely DL, San miguel GI, Hassan I, Schocken DD. J Clin Endocrinol Metab. 200186(9):4244-9. Characterization of neuropeptide Y-mediated corticotropin-releasing factor synthesis and release from human placental trophoblasts. Robidoux J, Simoneau L, St-pierre S, Masse A, Lafond J. Endocrinology. 2000141(8):2795-804.

Related Research Products & Support

For complementary laboratory workflows, explore related items in our catalog: BNP-32 (Canine) – Fluorescent EIA Kit, BNP-32 (Canine) – EIA Kit, and BNP-32 (Canine) – Chemiluminescent EIA Kit available through Phoenix Peptide. Guaranteed for quality assurance and analytical precision.

Specification / Feature	Details
Catalog Number	RK-019-06
Packaging	125 tubes
Category	ELISA Kits – Assay Kits – RIA Kits
Price / Unit	$942
Intra-Assay CV:	<10%
Inter-Assay CV:	<15%
Sensitivity:	100.1 pg/ml
Specificity:	Peptide %
CRF (Human, Rat)	100
CRF (Ovine)	1.8
ACTH (Human)	0
LH-RH	0
PACAP-38 (Human, Rat, Ovine)	0
[Arg 8 ]-Vasopressin	0
Urocortin (Human)	0
Urocortin (Rat)	0
BNP-45 (Rat)	0
Standard Range:	10 – 1280 pg/ml
Radioactivity:	Each kit contains 1.5 µCi of Iodine 125.