Angiotensin II (Human, Rat, Mouse, Porcine, Canine, Guinea Pig, Rabbit) – RIA Kit

The Angiotensin II (Human, Rat, Mouse, Porcine, Canine, Guinea Pig, Rabbit) – RIA Kit (Catalog #RK-002-12) is a research reagent supplied by Phoenix Peptide under our specialized ELISA Kits – Assay Kits – RIA Kits category. This item is offered at a regular price of $991 for a package size of 125 tubes.

Storage, Handling & Operational Notes

Transport & Regulatory Notes: This package conforms to the 49 CFR173.421 for expected radioactive material limited quantity, N.O.S. UN2910.

References & Citations: Activation of systemic, but not local, renin-angiotensin system is associated with upregulation of TNF-α during prolonged fasting in northern elephant seal pups. Suzuki M, Vázquez-medina JP, Viscarra JA, Soñanez-organis JG, Crocker DE, Ortiz RM. J Exp Biol. 2013216(Pt 17):3215-21. Angiotensin receptor blockade recovers hepatic UCP2 expression and aconitase and SDH activities and ameliorates hepatic oxidative damage in insulin resistant rats. Montez P, Vázquez-medina JP, Rodríguez R, et al. Endocrinology. 2012153(12):5746-59. Inhibition of ADP-ribosyl cyclase attenuates angiotensin II-induced cardiac hypertrophy. Gul R, Park JH, Kim SY, et al. Cardiovasc Res. 200981(3):582-91. Leptin, a novel predictor of lung function in heart failure. Sierra-johnson J, Romero-corral A, Somers VK, Olson LJ, Johnson BD. Chest. 2008134(2):346-50. Chronic ACE inhibitor treatment increases angiotensin type 1 receptor binding in vivo in the dog kidney. Zober TG, Fabucci ME, Zheng W, et al. Eur J Nucl Med Mol Imaging. 200835(6):1109-16. Treatment of sepsis-induced acquired protein C deficiency reverses Angiotensin-converting enzyme-2 inhibition and decreases pulmonary inflammatory response. Richardson MA, Gupta A, O’brien LA, et al. J Pharmacol Exp Ther. 2008325(1):17-26. The renin-angiotensin system contributes to renal fibrosis through regulation of fibrocytes. Sakai N, Wada T, Matsushima K, et al. J Hypertens. 200826(4):780-90. Improvement of stunned myocardium in dogs with olmesartan, an angiotensin II type 1 receptor antagonist, is independent of type 2 receptors. Kano S, Satoh K, Kaneta S, Ichihara K. Pharmacology. 200882(1):22-9. Purinergic receptors contribute to early mesangial cell transformation and renal vessel hypertrophy during angiotensin II-induced hypertension. Graciano ML, Nishiyama A, Jackson K, et al. Am J Physiol Renal Physiol. 2008294(1):F161-9. Differential effect of tetradecythioacetic acid on the renin-angiotensin system and blood pressure in SHR and 2-kidney, 1-clip hypertension. Bivol LM, Berge RK, Iversen BM. Am J Physiol Renal Physiol. 2007293(3):F839-45. Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2. Gupta A, Rhodes GJ, Berg DT, Gerlitz B, Molitoris BA, Grinnell BW. Am J Physiol Renal Physiol. 2007293(1):F245-54. Do cardiac neuropeptides play a role in the occurrence of atrial fibrillation after coronary bypass surgery?. Guler N, Ozkara C, Dulger H, et al. Ann Thorac Surg. 200783(2):532-7. Angiotensin II and aldosterone increase with fasting in breeding adult male northern elephant seals (Mirounga angustirostris). Ortiz RM, Crocker DE, Houser DS, Webb PM. Physiol Biochem Zool. 200679(6):1106-12. The effects of angiotensin-converting enzyme inhibition on the urinary excretion of NTproBNP in male volunteers. Heringlake M, Will B, Klaus S, et al. Kidney Blood Press Res. 200629(5):294-305. Blood volume expansion and cardiorespiratory function: effects of training modality. Warburton DE, Haykowsky MJ, Quinney HA, et al. Med Sci Sports Exerc. 200436(6):991-1000. Chymase-like angiotensin II-generating activity in end-stage human autosomal dominant polycystic kidney disease. Mcpherson EA, Luo Z, Brown RA, et al. J Am Soc Nephrol. 200415(2):493-500. 1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. Li YC, Kong J, Wei M, Chen ZF, Liu SQ, Cao LP. J Clin Invest. 2002110(2):229-38. Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat. Zimpelmann J, Kumar D, Levine DZ, et al. Kidney Int. 200058(6):2320-30.

Related Research Products & Support

For complementary laboratory workflows, explore related items in our catalog: prepro-Motilin, C-terminal (Human) – EIA Kit, CE Mark Certified, prepro-Motilin, C-terminal (Human) – EIA Kit, and Motilin (Human, Porcine) – RIA Kit available through Phoenix Peptide. Guaranteed for quality assurance and analytical precision.

Specification / Feature	Details
Catalog Number	RK-002-12
Packaging	125 tubes
Category	ELISA Kits – Assay Kits – RIA Kits
Price / Unit	$991
Intra-Assay CV:	<10%
Inter-Assay CV:	<15%
Sensitivity:	~20 pg/ml
Specificity:	Peptide %
Angiotensin II (Human, Rat, Mouse, Canine)	100
Angiotensin III (Human)	100
Preangiotensin (1-14)	1
Angiotensin I (Human, Rat, Mouse, Canine)	1
Angiotensin II (1-4) (Human)	0
Angiotensin II (5-8) (Human)	0
ACTH (Human)	0
Endothelin-1 (Human, Porcine, Rat)	0
[Arg 8 ]-Vasopressin	0
Standard Range:	5 – 640 pg/ml
Radioactivity:	Each kit contains 1.5 µCi of Iodine 125.