Endothelin 1 (ET-1) (Human, Rat, Mouse, Porcine, Bovine, Canine, Rabbit, Monkey) – RIA Kit

The Endothelin 1 (ET-1) (Human, Rat, Mouse, Porcine, Bovine, Canine, Rabbit, Monkey) – RIA Kit (Catalog #RK-023-01) is a research reagent supplied by Phoenix Peptide under our specialized ELISA Kits – Assay Kits – RIA Kits category. This item is offered at a regular price of $942 for a package size of 125 tubes.

Storage, Handling & Operational Notes

Transport & Regulatory Notes: This package conforms to the 49 CFR173.421 for expected radioactive material limited quantity, N.O.S. UN2910.

References & Citations: tPA-S(481)A prevents impairment of cerebrovascular autoregulation by endogenous tPA after traumatic brain injury by upregulating p38 MAPK and inhibiting ET-1. Armstead WM, Bohman LE, Riley J, Yarovoi S, Higazi AA, Cines DB. J Neurotrauma. 201330(22):1898-907. Pentoxifylline attenuation of experimental hepatopulmonary syndrome. Zhang J, Ling Y, Tang L, et al. J Appl Physiol. 2007102(3):949-55. 17beta-estradiol inhibits endothelin-1 production and attenuates cerebral vasospasm after experimental subarachnoid hemorrhage. Lin CL, Dumont AS, Wu SC, et al. Exp Biol Med (Maywood). 2006231(6):1054-7. Regulation of the rat brain endothelin system by endogenous beta-endorphin. Wang X, Xu H, Rothman RB. Peptides. 200627(4):769-74. Expression of endothelin-1 system in a pig model of endotoxic shock. Forni M, Mazzola S, Ribeiro LA, et al. Regul Pept. 2005131(1-3):89-96. Cholangiocyte endothelin 1 and transforming growth factor beta1 production in rat experimental hepatopulmonary syndrome. Luo B, Tang L, Wang Z, et al. Gastroenterology. 2005129(2):682-95. Ghrelin blunted vascular calcification in vivo and in vitro in rats. Li GZ, Jiang W, Zhao J, et al. Regul Pept. 2005129(1-3):167-76. Effects of magnesium sulfate on lipid peroxidation and blood pressure regulators in preeclampsia. Ariza AC, Bobadilla N, Fernández C, Muñoz-fuentes RM, Larrea F, Halhali A. Clin Biochem. 200538(2):128-33. ET-1 and TNF-alpha in HPS: analysis in prehepatic portal hypertension and biliary and nonbiliary cirrhosis in rats. Luo B, Liu L, Tang L, Zhang J, Ling Y, Fallon MB. Am J Physiol Gastrointest Liver Physiol. 2004286(2):G294-303. Triiodothyronine increases brain natriuretic peptide (BNP) gene transcription and amplifies endothelin-dependent BNP gene transcription and hypertrophy in neonatal rat ventricular myocytes. Liang F, Webb P, Marimuthu A, Zhang S, Gardner DG. J Biol Chem. 2003278(17):15073-83. Adrenomedullin inhibits the endothelin production induced by urotensin II inr at vascular smooth muscle cells. Qi Y, Bu D, Yanh J, et al. Chinese Science Bulletin. 200247(17):1457-61. Biliary cyst fluid from common bile duct-ligated rats stimulates endothelial nitric oxide synthase in pulmonary artery endothelial cells: a potential role in hepatopulmonary syndrome. Liu L, Zhang M, Luo B, Abrams GA, Fallon MB. Hepatology. 200133(3):722-7. Acute endothelin A receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure. Givertz MM, Colucci WS, Lejemtel TH, et al. Circulation. 2000101(25):2922-7. Modulation of functionally active endothelin-converting enzyme by chronic neutral endopeptidase inhibition in experimental atherosclerosis. Grantham JA, Schirger JA, Wennberg PW, et al. Circulation. 2000101(16):1976-81. Intra-atrial communication and control of atrial natriuretic factor (ANF) release. Deng Y, Zhang Y, Lang M, Kaufman S. Can J Physiol Pharmacol. 200078(1):1-6. Contribution of the endothelin system to the renal hypoperfusion associated with experimental congestive heart failure. Friedrich EB, Muders F, Luchner A, Dietl O, Riegger GA, Elsner D. J Cardiovasc Pharmacol. 199934(4):612-7.

Related Research Products & Support

For complementary laboratory workflows, explore related items in our catalog: Somatostatin (Human, Rat, Mouse, Porcine) – EIA Kit, CE Mark Certified, Somatostatin (Human, Rat, Mouse, Porcine) – EIA Kit, and Somatostatin (Human, Rat, Mouse, Porcine) – Chemiluminescent EIA Kit available through Phoenix Peptide. Guaranteed for quality assurance and analytical precision.

Specification / Feature	Details
Catalog Number	RK-023-01
Packaging	125 tubes
Category	ELISA Kits – Assay Kits – RIA Kits
Price / Unit	$942
Intra-Assay CV:	<10%
Inter-Assay CV:	<15%
Sensitivity:	53.2 pg/ml
Specificity:	Peptide %
Endothelin-1 (Human, Rat, Mouse, Porcine, Bovine, Canine, Rabbit, Monkey)	100
Endothelin-2 (Human, Canine)	100
Big Endothelin-2 (Human)	100
Big Endothelin-1 (Human)	76
Endothelin-3 (Human, Rat, Porcine)	0
Angiotensin II (Human)	0
Urotensin II (Human)	0
Standard Range:	10 – 1280 pg/ml
Radioactivity:	Each kit contains 1.5 µCi of Iodine 125.